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Vitamin d from dietary intake or sun exposure requires two activation steps in the body. The first activation occurs in the liver, while the second activation occurs in the kidneys, allowing for regulation of calcium metabolism. However, vitamin d receptors are present throughout the body, in tissue such as the skin, cartilage, heart, prostate, bones and intestines. Thus, the second activation step also takes place in local tissues. Recent discoveries have highlighted the important modulatory effects of vitamin d on various cells of the immune system.vitamin d enhances and regulates immune function. It is known that various cells of the immune system, such as t lymphocytes and antigen presenting cells, express the vitamin d receptor on their surface when activated. Recently, it has been found that treatment of these immune cells with vitamin d influences their expression of cytokines, which are chemical messengers of the immune system. The immune modulating effects of vitamin d extend to monocytes and dendritic cells of the immune system as well. Dendritic cells are important antigen-processing cells of the immune system that function to initiate the immune response. Vitamin d may prevent overactivity of the immune response and keep the immune system in a normal healthy state of vigilance.vitamin d supports optimal cardiovascular function. Research has uncovered the role vitamin d plays in supporting cardiac function. Heart myocytes (cells) express the vitamin d receptor, as do smooth muscle cells of blood vessels. The benefits of vitamin d on the heart are potentially far-reaching. Studies on mice heart cells have shown that vitamin d administration impacts their growth and proliferation. In these cells, vitamin d inhibited the release of a protein that could be detrimental to the function of these cells, displaying cardioprotective properties. It has also been shown that vitamin d has a modulatory effect on heart rhythm.
Is Discontinued By Manufacturer:No
Product Dimensions:2.19 x 2.19 x 4.25 inches; 3.84 Ounces
Item model number:DRB-00250
Date First Available:May 18, 2011
Manufacturer:Doctor’s Best
ASIN:B0050MYHBQ
Country of Origin:USA
Domestic Shipping:Currently, item can be shipped only within the U.S. and to APO/FPO addresses. For APO/FPO shipments, please check with the manufacturer regarding warranty and support issues.International Shipping:This item can be shipped to select countries outside of the U.S. Learn More
Benefits of vitamin D3 – enhances and regulates immune function, supports optimal cardiovascular function and enhances cellular function
Get your needed daily dose – Approximately 75% of Americans are deficient in vitamin D. Some researchers suggest that a minimum daily intake of 1,000 IU is necessary to maintain barely adequate blood levels of vitamin D. Others agree that much higher doses are needed to ensure levels are optimal enough to promote health.
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